Oral History as a Source for the Interpretation of UBH: The World War II Shelters in Naples Case Study

What can be the contribution of oral history to the interpretation of tangible cultural assets? Starting from this conceptual question, this article focuses on the case study of the experiences Second World War in Naples bomb shelters, recently included within the Underground Built Heritage (UBH) class. The hypothesis of the research is that bomb shelters are very significant elements in the subsoil of Naples but that, due to the lack of distinctive elements and dedicated storytelling, they are only partially exploited in the context of urban parks or generic itineraries Naples's subsoil. The thesis of the research is that the memories of those children that took refuge there during World War II (WWII), which were collected with the adoption of the oral history methodology, can integrate their value as elements of local cultural heritage and eventually support their interpretation for the benefit of the new generations. The methodology adopted was the collection, via structured and unstructured interviews, of the direct testimonies of those who took refuge in Naples' underground during the alarms. Twenty-three interviews were carried out, and all the issues introduced have been classified according to the various themes addressed during the narration in order to allow the reconstruction of dedicated storytelling in the future. The research was carried out immediately after the acute phase of the COVID-19 pandemic, an event that claimed many victims belonging to the generation of our witnesses, whose memories were at risk of being lost forever. © 2023 by the author.

Emerging Key Elements of a Business Model for Sustaining the Cultural and Creative Industries in the Post-Pandemic Era

In this article, the challenges that cultural and creative industry (CCI) firms face in forming sustainable business models—issues heightened by the ongoing COVID-19 pandemic and the evolving consumer patterns that it has triggered—are addressed. The goal of this study was to identify a set of unique key elements crucial for the construction of a business model that aligns with the distinct characteristics of CCIs. To achieve this goal, an in-depth, long-term study using semi-structured interviews with proprietors in Eastern Taiwan was conducted. This region is home to unique, small-scale cultural and creative businesses and represents less than 5% of Taiwan's population. The semi-structured, in-depth interviews served as the data collection method, while content analysis was used for data interpretation. This approach allowed the current study to encapsulate a set of key elements that could inform the creation of a business model for CCI firms. The insights gathered by the study provide a robust framework for the development of sustainable CCI business models, offering valuable guidance for both existing businesses seeking to adapt and grow and new entrepreneurs entering the industry. This research also aims to stimulate further scholarly debate on the importance of a tailored, multidisciplinary business model for CCIs, given their unique needs and characteristics.

Online Contingent Attention Training (OCAT): transfer effects to cognitive biases, rumination, and anxiety symptoms from two proof-of-principle studies.

The aim of the present research was to develop and test the efficacy of a novel online contingent attention training (i.e., OCAT) to modify attention and interpretation biases, improve emotion regulation, and reduce emotional symptom levels in the face of major stressors. Two proof-of-principle studies were carried out. In study 1, 64 undergraduates who were about to start a major stressful period (i.e., final exams) were randomized to undergo 10 days of active OCAT or a sham-control training. Emotion regulation (habitual use of rumination and reappraisal) and symptom levels (depression and anxiety) were assessed before and after the intervention. In study 2, the same 2 × 2 mixed design was used with 58 individuals from the general population undergoing a major stressful situation (the lockdown period at the beginning of the COVID-19 pandemic in 2020). In both studies, the OCAT group showed significant improvements on attention towards negative information and interpretation biases in comparison to the sham-control group. Additionally, changes in cognitive biases transferred to reductions of participants' use of rumination and anxiety symptom levels. These results show preliminary evidence regarding the efficacy of the OCAT to target attention and interpretation biases as well as to improve emotion regulation processes and to buffer against the effects of major stressors.

Dual-role nurse interpreter perceptions of language barriers and Spanish-speaking patients: A qualitative study.

AIM: As the United States population is ever changing and is growing in diverse population patterns, the health care system is called to initiate responsive health care practices that are based on the public's changing and diverse cultural patterns. This study sought to explore the perceptions of certified medical interpreter dual-role nurses and their experiences with Spanish-speaking patients from admission to discharge in hospital stays. DESIGN: A qualitative descriptive case study was applied in this study. METHODS: Data was collected from nurses working at a United States Southwest Borderland hospital using purposive sampling and semi-structured in-depth interviews. A total of four dual-role nurses participated, and thematic narrative analysis was applied. RESULTS: Four major themes emerged. The main themes were "being a dual-role nurse interpreter," "patient experience," "culture and competence, "and "nursing and caring," With each major theme multiple sub themes emerged. Two sub themes emerged with "being a dual-role nurse interpreter," and two sub themes emerged with "patient experiences." The major themes that emerged from the interviews indicated that the language barrier greatly affects Spanish-speaking patients in their hospital stay. Participants reported having at least one encounter with a Spanish-speaking patient that was not afforded interpretation services or had interpretation from someone other than a qualified interpreter. Patients experienced confusion, apprehension and anger associated with not being able to communicate their needs to the healthcare system. CONCLUSIONS: According to the experiences of the certified dual-role nurse interpreters, having a language barrier makes a tremendous impact on the care of Spanish-speaking patients. Nurse participants describe how patients and their family members experience dissatisfaction, anger and confusion when there is a language barrier and most importantly how language barriers have detrimental effects on patients with wrong medication prescriptions and wrong diagnosis. CLINICAL RELEVANCE: When hospital administration recognize and support nurses as certified medical interpreters as a key component for patient care when assisting persons with limited English proficiency, patients are empowered to become active members of their healthcare regimen. The role of dual-role nurses enables brokering between the healthcare system and serves as a tool to bridge health disparities based on linguistic inequities existing in healthcare. Recruitment and retention of certified medical interpreter trained Spanish-speaking nurses deter errors in healthcare and makes a positive impact on the healthcare regimen of Spanish-speaking patients enabling patient empowerment through education and advocacy.

Predictors of Evacuation Rates during Hurricane Laura: Weather Forecasts, Twitter, and COVID-19

Machine learning was applied to predict evacuation rates for all census tracts affected by Hurricane Laura. The evacuation ground truth was derived from cellular telephone–based mobility data. Twitter data, census data, geographical data, COVID-19 case rates, the social vulnerability index from the Centers for Disease Control and Prevention (CDC)/Agency for Toxic Substances and Disease Registry (ATSDR), and relevant weather and physical data were used to do the prediction. Random forests were found to perform well, with a mean absolute percent error of 4.9% on testing data. Feature importance for prediction was analyzed using Shapley additive explanations and it was found that previous evacuation, rainfall forecasts, COVID-19 case rates, and Twitter data rank highly in terms of importance. Social vulnerability indices were also found to show a very consistent relationship with evacuation rates, such that higher vulnerability consistently implies lower evacuation rates. These findings can help with hurricane evacuation preparedness and planning as well as real-time assessment. © 2023 American Meteorological Society.

The impossibility of freedom: From psychoanalytical conceptions to political objections

This chapter provides an overview of psychoanalytical conceptions on freedom is provided along with certain political objections. Urukagina's code has been widely hailed as the first recorded specimen of government reform, seeking to achieve a higher level of freedom and equality. The chapter encounters conical shape associated with freedom in Ancient Rome: pileus. Liberty embodies the privileges of independence, freedom, on the other hand, the rights of belonging. To top it all off, in countries with authoritarian regimes, quarantine-like regulations that are dictated by the COVID-19 pandemic created an opportunity for restricting freedom of speech and freedom of peaceful assembly. Ego is neither able to control passion nor the external world in the name of reason or freedom. Through a newly won freedom from the constraints of fantasy, the course of a psychoanalysis should enable the person to approach reality from a different perspective, to pass from the restrictions of an unconscious internal reality to the possibilities offered by whatever may happen. Consistent with his aim, Freud saw freedom as an illusion and redefined it as the recognition of necessity. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

The Missing Strategy in Addressing Language Barriers

By following the 3 points below, health care leaders can improve their health care delivery practices for patients with limited English proficiency: * improve health care delivery for populations with limited English proficiency, * partner with community-based organizations that teach ESL, and * leverage Medicaid and work with insurers to better manage the care of non–English-speaking patients. _____ Coronavirus disease 2019 (COVID-19) mortality data show that Latinxs are disproportionately dying in the United States.1 These findings parallel known health disparities for Latinxs, which can be attributed in part to language barriers. When patients and their clinicians do not speak the same language, patients receive less health education and experience more testing, more readmissions, and longer lengths of stay, resulting in higher health care utilization.3 Beyond the clinical setting, language, like other social determinants of health, affects patients' lived environments, including their ability to understand food labels, apply for public housing services, and access reliable community health information. Funding could also be sought through the reintroduction of an Obama administration federal proposal that supported partnerships among states, adult education providers, higher education institutions, and private organizations.9 Bolstering language services with health-focused ESL courses may ultimately reduce health care spending and satisfy mandatory community health needs assessment implementation strategies. Health systems can then evaluate the effectiveness of their courses internally or by partnering with the Department of Education, which provides funds for evaluation of adult education programs.11 Access to health-focused ESL classes can be improved, but participation can still be hindered by day-to-day patient barriers, such as working multiple jobs and lacking transportation. [...]ESL programs should not be implemented in isolation but rather as part of a larger infrastructure focused on addressing patients' social needs.

Dreaming for the World: A Jungian Study of Dreams During the COVID‐19 Pandemic

This project explores what dreams might reveal about the collective psyche’s response to the COVID‐19 pandemic in its first year, before the development of vaccines. A brief survey, distributed to Jungian colleagues and organizations, and to various social media sites, invited people to submit online a dream related to the COVID‐19 pandemic. Four hundred and thirty‐six dreams were submitted. Forty additional Russian dreams were collected and submitted by Russian colleagues. Using qualitative research methods based on phenomenological hermeneutics, the researchers categorized and counted the range of COVID imagery. In addition, the researchers describe a range of psychic responses to the pandemic, including horror, grief, sickness, social discord, and violence, but also images of healing and transformation, increased sense of community, and spiritual renewal. Several healing nightmares are presented. Healing alchemical and anima/animus imagery is described. Twelve dreams are introduced and presented. It is concluded that the collective psyche, rooted in the Self, is a healing resource for social and cultural trauma. This project supports Beradt’s (1968) inspirational study of dreaming in Nazi Germany, as well as recent studies of COVID‐related dreams and recent publications on the social nature of dreaming.Alternate :Ce projet explore ce que les rêves peuvent révéler en ce qui concerne la réponse de la psyché collective à la pandémie de COVID‐19 dans sa première année, avant le développement des vaccins. Un court questionnaire, distribué à des collègues et des organisations Jungiennes, et à divers sites de réseaux sociaux, invitait les personnes à mettre en ligne un rêve en lien avec la pandémie de COVID‐19. Quatre cent trente‐six rêves ont été mis en ligne. D’autre part quarante rêves ont été collectés et mis en ligne par des collègues Russes. En utilisant les méthodes de recherche qualitative fondées sur l’herméneutique phénoménologique, les chercheurs ont établi des catégories et ont dénombré la variété de l’imagerie liée au COVID. De plus, les chercheurs ont décrit un certain nombre de réponses psychiques à la pandémie, par exemple l’horreur, le chagrin, la maladie, la discorde sociale et la violence, mais également des images de guérison et de transformation, un sentiment accru de communauté, et du renouveau spirituel. Plusieurs cauchemars de guérison sont présentés. L’imagerie de la guérison alchimique et celle liée à l’anima/animus est décrite. Douze rêves sont décrits et présentés. La conclusion apportée est que la psyché collective, enracinée dans le Soi, est une ressource de guérison en ce qui concerne le traumatisme social et culturel. Ce projet soutient l’étude inspirante de Beradt (1968) de rêves dans l’Allemagne Nazie, ainsi que des études récentes de rêves en lien avec la COVID et des publications récentes sur la nature sociale du rêve.Alternate :Dieses Projekt untersucht, was Träume über die Reaktion der kollektiven Psyche auf die COVID‐19‐Pandemie im ersten Jahr vor der Entwicklung von Impfstoffen verraten könnten. Eine kurze Umfrage, die an Jungianische Kollegen und Organisationen sowie an verschiedene Social‐Media‐Sites verteilt wurde, lud Menschen ein, online einen Traum im Zusammenhang mit der COVID‐19‐Pandemie einzureichen. Vierhundertsechsunddreißig Träume wurden eingereicht. Vierzig weitere russische Träume wurden gesammelt und von russischen Kollegen zugesandt. Unter Verwendung qualitativer Forschungsmethoden auf der Grundlage phänomenologischer Hermeneutik kategorisierten und zählten die Forscher die Bandbreite der COVID‐Bilder. Darüber hinaus beschreiben die Forscher eine Reihe psychischer Reaktionen auf die Pandemie, darunter Entsetzen, Trauer, Krankheit, soziale Zwietracht und Gewalt, aber auch Bilder von Heilung und Transformation, gesteigertem Gemeinschaftsgefühl und spiritueller Erneuerung. Mehrere heilende Albträume werden präsentiert. Heilend alchemistische und Anima/Animus‐Bilder werden beschrieben. Zwölf Träume werden vorgestellt und präsentiert. Es wird der Schluß gezogen, daß die im Selbst verwurzelte kollektive Psyche eine heilende Ressource für soziale und kulturelle Traumata darstellt. Dieses Projekt unterstützt Beradts (1968) inspirierende Studie über das Träumen in Nazi‐Deutschland sowie neuere Studien zu COVID‐bezogenen Träumen und neuere Veröffentlichungen über die soziale Natur des Träumens.Alternate :Questo progetto esplora cosa possono rivelare i sogni sulla risposta della psiche collettiva alla pandemia di COVID‐19 nel suo primo anno, prima dello sviluppo dei vaccini. Un breve sondaggio, distribuito a colleghi e organizzazioni junghiane, e a vari siti di social media, ha invitato le persone a presentare online un sogno legato alla pandemia di COVID‐19. Sono stati inviati 436 sogni. Altri quaranta sogni russi sono stati raccolti e inviati da colleghi russi. Usando metodi di ricerca qualitativa basati sull’ermeneutica fenomenologica, i ricercatori hanno categorizzato e contato l’assortimento dell’immaginario relativo al COVID‐19. Inoltre, i ricercatori descrivono una serie di risposte psichiche alla pandemia, incluso orrore, dolore, malattia, tensione sociale e violenza, ma anche immagini di guarigione e trasformazione, maggiore senso di comunità , e rinnovamento spirituale. Vengono presentati diversi incubi che sono stati terapeutici. Vengono descritte la guarigione alchemica e le immagini di anima/animus. Vengono introdotti e presentati dodici sogni. Gli Autori concludono che la psiche collettiva, radicata nel Sé, è una risorsa curativa per il trauma sociale e culturale. Questo progetto supporta lo stimolante studio di Berardt (1968) sui sogni nella Germania nazista, così come studi recenti sui sogni legati al COVID‐19 e con le recenti pubblicazioni sulla natura sociale dei sogni.Alternate :Ð' этом проекте исследуется, что могут рассказать сновидения о реакции коллективной психики на пандемию COVID‐19 в течение первого года, до того, как были разработаны вакцины. Ð' краткой анкете, рассылавшейся юнгианским коллегам и организациям, а также размещенной в социальных сетях, респондентам предлагалось предоставить в электронном виде свои сновидения, связанные с пандемией COVID‐19. Было прислано четыреста тридцать шесть сновидений. Еще сорок сновидений на русском языке было собрано и предоставлено российскими коллегами. Используя качественные методы исследования, основанные на феноменологической герменевтике, исследователи произвели подсчеты и классификацию и получили диапазон образов COVID. Кроме того, исследователи описали целый ряд психологических реакций на пандемию, среди которых ужас, горе, заболевания, социальные разногласия и насилие, но вместе с тем и образы исцеления и трансформации, усиленное чувства общности и духовное обновление. Описывается ряд кошмарных сновиденийс целебным эффектом. Приведены исцеляющие алхимические образы анимы/анимуса. Подробно представлено двенадцать сновидений. Исследователи приходят к заключению, что Ñ€ÐµÑ ÑƒÑ€ÑÐ¾Ð¼ для исцеления социальных и культурных травм является коллективная психика, опирающаяся на Самость. Ð'ыводы проекта подтверждают результаты вдохновляющего исследования Берадта о сновидениях в нацистской Ð"ермании (1968), а также недавних исследований сновидений, связанных с COVID, и публикаций о социальной природе сновидений.Alternate :Este proyecto explora lo que los sueños podrían revelar sobre la respuesta de la psique colectiva a la pandemia de COVID‐19 en su primer año, antes del desarrollo de las vacunas. A través de una breve encuesta, distribuida entre colegas y organizaciones Junguianas, así como en diversas redes sociales, se invitó a la gente a enviar en línea un sueño relacionado con la pandemia de COVID‐19. Se presentaron 436 sueños. Otros cuarenta sueños rusos fueron posteriormente recogidos y enviados por colegas rusos. Utilizando métodos de investigación cualitativa basados en la hermenéutica fenomenológica, los investigadores categorizaron y contaron una gama de imágenes de COVID. Además, los investigadores describen una serie de respuestas psíquicas a la pandemia, que incluyen horror, dolor, enfermedad, discordia social y violencia, pero también imágenes de curación y transformación, aumento del sentido de comunidad y renovación espiritual. Se presentan varias pesadillas curativas. Se describen imágenes alquímicas curativas y de anima/animus. Se introducen y presentan doce sueños. Se concluye que la psique colectiva, enraizada en el Self, es un recurso curativo para el trauma social y cultural. Este proyecto apoya el inspirador estudio de Beradt (1968) sobre los sueños en la Alemania nazi, así como estudios recientes sobre los sueños relacionados con el COVID y con publicaciones recientes sobre la naturaleza social de los sueños.Alternate :为世界做梦:æ–°å† ç–«æƒ…æœŸé—´æ¢¦å¢ƒçš„è£æ ¼å­¦æ´¾ç ”ç©¶è¿™ä¸ªé¡¹ç›®æŽ¢è®¨äº†æ¢¦å¢ƒå¦‚ä½•æ­ç¤ºé›†ä½"心灵对COVID‐19疫情所做出的反应, 这些梦境发生在疫情第一年, åœ¨ç–«è‹—å¼€å‘ä¹‹å‰ã€‚æœ¬ç ”ç©¶å‘è£æ ¼å­¦æ´¾åŒè¡Œå'Œç»„织, 以及通过各种社会åª'ä½"网站分发了一份简短的调查, 邀请人们在线提交与COVID‐19疫情有关的梦。共收集到四百三十六个梦。另外还收集了40个俄罗斯人的梦, å¹¶ç”±ä¿„ç½—æ–¯åŒäº‹æäº¤ã€‚ç ”ç©¶ä½¿ç”¨äº†åŸºäºŽçŽ°è±¡å­¦è¯ é‡Šå­¦çš„å®šæ€§ç ”ç©¶æ–¹æ³•, ç ”ç©¶äººå‘˜å¯¹ä¸Žæ–°å† ç›¸å…³çš„æ„è±¡è¿›è¡Œäº†åˆ†ç±»å'Œç»Ÿè®¡ã€‚此外, ç ”ç©¶äººå‘˜è¿˜æè¿°äº†æ¢¦ä¸­äººä»¬å¯¹ç–«æƒ…åšå‡ºçš„ä¸€ç³»åˆ—å¿ƒç†ååº”, 包括恐怖、悲伤、疾病、社会不å'Œè°å'Œæš´åŠ›, 但也有治愈å'Œè½¬å˜çš„意象、增强的社区感å'Œç²¾ç¥žæ›´æ–°çš„æ„è±¡ã€‚ç ”ç©¶ä»‹ç»äº†å‡ ä¸ªå¸¦æœ‰æ²»æ„ˆæ€§çš„å™©æ¢¦ã€‚æè¿°äº†æ²»æ„ˆæ€§çš„ç‚¼é‡‘æœ¯å'Œé˜¿å°¼çŽ›/阿尼玛斯意象。介绍并展示了12个梦。ç»"论是, æ¤æ ¹äºŽ “自性”的集ä½"心灵是治疗社会å'Œæ–‡åŒ–创伤的一种资源。这个项目的ç»"果支持了Beradt(1968)在纳粹德国的梦境的é¼"èˆžäººå¿ƒçš„ç ”ç©¶ç»"æžœ, ä¹Ÿä¸Žæœ€è¿‘å…³äºŽæ–°å† æ¢¦å¢ƒç ”ç©¶çš„ç»"æžœ, 及最近发表的关于梦境的社会性质的ç»"果一致。

Analytical and qualitative investigation of COVID-19 mathematical model under fractional differential operator.

In the current article, we aim to study in detail a novel coronavirus (2019-nCoV or COVID-19) mathematical model for different aspects under Caputo fractional derivative. First, from analysis point of view, existence is necessary to be investigated for any applied problem. Therefore, we used fixed point theorem's due to Banach's and Schaefer's to establish some sufficient results regarding existence and uniqueness of the solution to the proposed model. On the other hand, stability is important in respect of approximate solution, so we have developed condition sufficient for the stability of Ulam-Hyers and their different types for the considered system. In addition, the model has also been considered for semianalytical solution via Laplace Adomian decomposition method (LADM). On Matlab, by taking some real data about Pakistan, we graph the obtained results. In the last of the manuscript, a detail discussion and brief conclusion are provided.

Posthumanist stylistics

I present a posthumanist approach to literary interpretation using stylistic analysis. It is posthumanist since i) digital cameras/audio-video resources and editing applications prompt multimodal readings of literary works unlikely from human intuition alone;ii) anthropocentrism in literary texts is defamiliarised. I highlight how stylistic analysis can be used productively for developing multimodal creativity in posthumanist reading by motivating audio-video edits and effects. I model using Anne Brontë's poem ‘Home' (1846). When read only with intuition, ‘Home' communicates young Brontë's yearning for her family home. In contrast, this article has a non-intuitive digital multimodal realisation of this poem where a young Californian stuck in London because of pandemic (Covid-19) travel restrictions yearns for her home state in the aftermath of wildfires linked to anthropogenic climate change. This posthumanist transformative reading, flagging the negative repercussions of humans for their planetary home, defamiliarises the poem's anthropocentric normality. Importantly, I show how stylistic analysis of ‘Home' motivates creative use of audio-visual edits and effects in the posthumanist multimodal reading. The article makes contrast with standard interpretive practice in stylistics (‘humanist stylistics'). It also reflects on the value of posthumanist stylistics for extending students' creative thinking in an educational context. © The Author(s) 2023.

Office 365: Microsoft Lists as a tool for a secure online second-line/systemic drug database

Pre-COVID our dermatology department had slightly fragmented and unreliable methods of storing the details of patients receiving second-line and systemic medications, such as immunosuppressive agents. Often, this information was held within individual Microsoft Excel worksheets on desktop PCs. At the onset of the COVID-19 pandemic in 2020, rapid access to this information was required to allow high-risk patients and shielding groups to be identified. We spent significant time updating and merging these separate files to form a single document. At that stage, multiuser updates and simultaneous working on a single document was not feasible, and there was often duplication and being 'locked out'. A multirow section of our newly combined document was also inadvertently deleted and could not be recovered. Thankfully, at an early stage of the COVID-19 pandemic, Microsoft 365 was rapidly adopted and rolled out in our health board. The aim was to provide a comprehensive, all-in-one digital workspace, including communications, cloud storage, backup and syncing, and productivity apps to aid working remotely and from home. Our department, in a tertiary teaching hospital, migrated to this software and it rapidly helped facilitate increased digital collaboration between clinical team members. It was recognized that its cloud storage capability would be a useful tool to help centralize and store an online, amendable patient database to record details of current and previous second- line treatments, and important information relating to shielding and COVID-19 risk status. One of the revamped application functions within Office 365 is Microsoft Lists. This offers real-time, online, secure functionality, with the ability to colour-code patients by drug, consultant and COVID-19 risk status. All members of our team have access, including administrative and clinical pharmacy staff, allowing each patient record to be easily accessed and updated. There is an additional functionality to allow email notifications of any updates (e.g. when made to specific patient entries) and even direct notification to associated stakeholders (such as government COVID-19 risk and shielding bodies). This set-up has also provided an ideal platform to allow research and clinical audit activities to be performed, which can be backwards formatted into Microsoft Excel, again for any data interpretation. Removed entries for patients no longer on second-line drugs can be automatically transferred to a linked archive list. In summary, this digital project highlights our departmental experience in using Microsoft Lists as an online, secure, cloud-based portal for patients on second-line medications and to record accurately COVID-19 risk status. It is easy to use, pleasing on the eye and its functionality could be transferrable to other clinical areas, such as in skin cancer or diagnosis logs.

"Covid vaccine is against Covid but Oxford vaccine is made at Oxford!” Semantic Interpretation of Proper Noun Compounds

Proper noun compounds, e.g., "Covid vaccine”, convey information in a succinct manner (a "Covid vaccine” is a "vaccine that immunizes against the Covid disease”). These are commonly used in short-form domains, such as news headlines, but are largely ignored in information-seeking applications. To address this limitation, we release a new manually annotated dataset, PRONCI, consisting of 22.5K proper noun compounds along with their free-form semantic interpretations. PRONCI is 60 times larger than prior noun compound datasets and also includes non-compositional examples, which have not been previously explored. We experiment with various neural models for automatically generating the semantic interpretations from proper noun compounds, ranging from few-shot prompting to supervised learning, with varying degrees of knowledge about the constituent nouns. We find that adding targeted knowledge, particularly about the common noun, results in performance gains of upto 2.8%. Finally, we integrate our model generated interpretations with an existing Open IE system and observe an 7.5% increase in yield at a precision of 85%. The dataset and code are available at https://github.com/dair-iitd/pronci. © 2022 Association for Computational Linguistics.

Definition, characteristics and methodological interpretation of Cochrane rapid reviews.

Since the COVID-19 outbreak, the number of studies using rapid reviews (RR) for rapid evidence-based decision-making has been increasing. RR can significantly improve the timeliness of evidence and play an important role in decision making. To clarify the definition of RR and standardize its application, the Cochrane RR Methodology Group defined RR in 2021 and published the evidence-based guidelines for RR methodology. To promote researchers' understanding of RR, standardize the application of RR methodology, and improve the overall quality of this type of research, this paper introduced the development history of RR and interpreted the definition, characteristics and methodological content of RR.Copyright © 2023 West China University of Medical Science. All rights reserved.

Definition, characteristics and methodological interpretation of Cochrane rapid reviews.

Since the COVID-19 outbreak, the number of studies using rapid reviews (RR) for rapid evidence-based decision-making has been increasing. RR can significantly improve the timeliness of evidence and play an important role in decision making. To clarify the definition of RR and standardize its application, the Cochrane RR Methodology Group defined RR in 2021 and published the evidence-based guidelines for RR methodology. To promote researchers' understanding of RR, standardize the application of RR methodology, and improve the overall quality of this type of research, this paper introduced the development history of RR and interpreted the definition, characteristics and methodological content of RR.Copyright © 2023 West China University of Medical Science. All rights reserved.

Linking Public Art to Research

Folkestone, Kent, has the largest urban outdoor exhibition of contemporary art in the United Kingdom. This permanent exhibition shows the work of forty-eight contemporary artists whose work is displayed throughout the town, with many pieces having been created for the specific site in which they are located. This article provides an introduction to and personal reflective commentary on some artworks within the collection at Folkestone and how they supported the author's thinking during the COVID-19 pandemic. Eight artworks are discussed with a commentary on how they linked to the themes within research into experiences of part-time undergraduates at a distance learning university.

IPs-GRUAtt: An attention-based bidirectional gated recurrent unit network for predicting phosphorylation sites of SARS-CoV-2 infection.

The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has generated tremendous concern and poses a serious threat to international public health. Phosphorylation is a common post-translational modification affecting many essential cellular processes and is inextricably linked to SARS-CoV-2 infection. Hence, accurate identification of phosphorylation sites will be helpful to understand the mechanisms of SARS-CoV-2 infection and mitigate the ongoing COVID-19 pandemic. In the present study, an attention-based bidirectional gated recurrent unit network, called IPs-GRUAtt, was proposed to identify phosphorylation sites in SARS-CoV-2-infected host cells. Comparative results demonstrated that IPs-GRUAtt surpassed both state-of-the-art machine-learning methods and existing models for identifying phosphorylation sites. Moreover, the attention mechanism made IPs-GRUAtt able to extract the key features from protein sequences. These results demonstrated that the IPs-GRUAtt is a powerful tool for identifying phosphorylation sites. For facilitating its academic use, a freely available online web server for IPs-GRUAtt is provided at http://cbcb.cdutcm.edu.cn/phosphory/.

Diagnostic accuracy of autoverification and guidance system for COVID-19 RT-PCR results.

Background: To date, most countries worldwide have declared that the pandemic of COVID-19 is over, while the WHO has not officially ended the COVID-19 pandemic, and China still insists on the personalized dynamic COVID-free policy. Large-scale nucleic acid testing in Chinese communities and the manual interpretation for SARS-CoV-2 nucleic acid detection results pose a huge challenge for labour, quality and turnaround time (TAT) requirements. To solve this specific issue while increase the efficiency and accuracy of interpretation, we created an autoverification and guidance system (AGS) that can automatically interpret and report the COVID-19 reverse transcriptase-polymerase chain reaction (RT-PCR) results relaying on computer-based autoverification procedure and then validated its performance in real-world environments. This would be conductive to transmission risk prediction, COVID-19 prevention and control and timely medical treatment for positive patients in the context of the predictive, preventive and personalized medicine (PPPM). Methods: A diagnostic accuracy test was conducted with 380,693 participants from two COVID-19 test sites in China, the Hong Kong Hybribio Medical Laboratory (n = 266,035) and the mobile medical shelter at a Shanghai airport (n = 114,658). These participants underwent SARS-CoV-2 RT-PCR from March 28 to April 10, 2022. All RT-PCR results were interpreted by laboratorians and by using AGS simultaneously. Considering the manual interpretation as gold standard, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were applied to evaluate the diagnostic value of the AGS on the interpretation of RT-PCR results. Results: Among the 266,035 samples in Hong Kong, there were 16,356 (6.15%) positive, 231,073 (86.86%) negative, 18,606 (6.99%) indefinite, 231,073 (86.86%, negative) no retest required and 34,962 (13.14%, positive and indefinite) retest required; the 114,658 samples in Shanghai consisted of 76 (0.07%) positive, 109,956 (95.90%) negative, 4626 (4.03%) indefinite, 109,956 (95.90%, negative) no retest required and 4702 (4.10%, positive and indefinite) retest required. Compared to the fashioned manual interpretation, the AGS is a procedure of high accuracy [99.96% (95%CI, 99.95-99.97%) in Hong Kong and 100% (95%CI, 100-100%) in Shanghai] with perfect sensitivity [99.98% (95%CI, 99.97-99.98%) in Hong Kong and 100% (95%CI, 100-100%) in Shanghai], specificity [99.87% (95%CI, 99.82-99.90%) in Hong Kong and 100% (95%CI, 99.92-100%) in Shanghai], PPV [99.98% (95%CI, 99.97-99.99%) in Hong Kong and 100% (95%CI, 99.99-100%) in Shanghai] and NPV [99.85% (95%CI, 99.80-99.88%) in Hong Kong and 100% (95%CI, 99.90-100%) in Shanghai]. The need for manual interpretation of total samples was dramatically reduced from 100% to 13.1% and the interpretation time fell from 53 h to 26 min in Hong Kong; while the manual interpretation of total samples was decreased from 100% to 4.1% and the interpretation time dropped from 20 h to 16 min at Shanghai. Conclusions: The AGS is a procedure of high accuracy and significantly relieves both labour and time from the challenge of large-scale screening of SARS-CoV-2 using RT-PCR. It should be recommended as a powerful screening, diagnostic and predictive system for SARS-CoV-2 to contribute timely the ending of the COVID-19 pandemic following the concept of PPPM.

Wellens Syndrome: A Possible Precursor.

Wellens syndrome is a precursor of left anterior descending (LAD) coronary stenosis. It is characterized by biphasic T waves in V2-V3 (type A) or negative deep T waves in V2-V4 (type B). The ability of emergency physicians, hospitalists, or primary care providers to recognize these early ECG patterns is primordial because the definitive treatment is urgent cardiac catheterization with percutaneous coronary intervention. However, failure to identify a type A or type B Wellens syndrome may lead to devastating outcomes, such as myocardial infarction or even death. We presented a clinical case of Wellens' syndrome with deep T waves in V2-V3 associated with COVID pneumonia, pleural effusions, and congestive heart failure that went to a rapid and massive myocardial infarction.

Live Mammographic Screening Interpretation Versus Offline Same-Day Screening Interpretation at a Tertiary Cancer Center.

OBJECTIVES: The aim of this study was to compare screening mammography performance metrics for immediate (live) interpretation versus offline interpretation at a cancer center. METHODS: An institutional review board-approved, retrospective comparison of screening mammography metrics at a cancer center for January 1, 2018, to December 31, 2019 (live period), and September 1, 2020, to March 31, 2022 (offline period), was performed. Before July 2020, screening examinations were interpreted while patients waited (live period), and diagnostic workup was performed concurrently. After the coronavirus disease 2019 shutdown from March to mid-June 2020, offline same-day interpretation was instituted. Patients with abnormal screening results returned for separate diagnostic evaluation. Screening metrics of positive predictive value 1 (PPV1), cancer detection rate (CDR), and abnormal interpretation rate (AIR) were compared for 17 radiologists who interpreted during both periods. Statistical significance was assessed using χ2 analysis. RESULTS: In the live period, there were 7,105 screenings, 635 recalls, and 51 screen-detected cancers. In the offline period, there were 7,512 screenings, 586 recalls, and 47 screen-detected cancers. Comparison of live screening metrics versus offline metrics produced the following results: AIR, 8.9% (635 of 7,105) versus 7.8% (586 of 7,512) (P = .01); PPV1, 8.0% (51 of 635) versus 8.0% (47 of 586); and CDR, 7.2/1,000 versus 6.3/1,000 (P = .50). When grouped by >10% AIR or <10% AIR for the live period, the >10% AIR group showed a significant decrease in AIR for offline interpretation (from 12.7% to 9.7%, P < .001), whereas the <10% AIR group showed no significant change (from 7.4% to 6.7%, P = .17). CONCLUSIONS: Conversion to offline screening interpretation from immediate interpretation at a cancer center was associated with lower AIR and similar CDR and PPV1. This effect was seen largely in radiologists with AIR > 10% in the live setting.